KaloBios’ Human 'Acceptor' Library
The donors for the KaloBios libraries are of diverse ethnic origin.. Using proprietary techniques, the libraries captured incomplete V regions from peripheral blood lymphocytes and spleen. Because the library was biased for the capture of IgM sequences, near-germline sequences are well represented in the Acceptor Library. Shown below is the ratio of different VH and VL (kappa and lambda) subclasses.
Pipeline
KaloBios' pipeline is comprised of first or best-in-class antibody therapeutic candidates for cancers.